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Nursing Assessment Guideline Evidence table. Routine Post Anaesthetic Observation Guideline Evidence Table Please remember to read the disclaimer. The development of this nursing guideline was coordinated by Stacey Richards, Nursing Research, CNC, and approved by the Nursing Clinical Effectiveness Committee. Updated November 2019.
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2. Primary intravenous (IV) injection site for the mouse is the right and left lateral tail vein. Other sites (e.g., retro-orbital [RO] sinus) require sedation and/or analgesia. 3. Please refer to the Guidelines for Injections in Rodents and Rabbits, Virginia Tech Office of the University Veterinarian for recommended volumes and needles sizes. a.
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Coordinator to assure training requirements are met in accordance to IACUC Policy. 4. Attending veterinarian and/or designee: a. Provide guidance/oversight on surgery programs and post-surgical care. b. Provide consultation services to investigators on the appropriate choice of anesthetic and analgesic agents.
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Anesthesia and Analgesia in Laboratory Animals focuses entirely on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Sponsored by the American College of Laboratory Animal Medicine, this informative work provides the reader with agents, methods, and techniques for anesthesia and ...
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Multimodal analgesia that combines an anti-inflammatory analgesic (NSAID) with an opioid (most often: buprenorphine) and a local anesthetic-analgesic (bupivacaine or lidocaine) is recommended. Balanced anesthesia that includes agents with analgesic activity (ketamine, opioids, alpha-2 adrenergics) is also recommended.
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A. Inspect the animal facilities at the time of each protocol submission. B. Assist with writing the basic science portions of a grant application. C. Conduct reviews of the animal care and use program on a semiannual basis. D. Write animal use protocols for investigators.
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CMDC #086.10 Effective 5/19 Page 1 of 22 . GUIDELINES ON ANESTHESIA AND ANALGESIA IN LABORATORY ANIMALS . University of South Florida provides the following guidelines for use by IACUC-certified faculty and staff.
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28/11/2014· Analgesia. All mice scoring greater than 3/50 on the welfare scoring system were defined as ‘in pain’ and received an extra dose of 0.012 mg of buprenorphine s.c. [average dose, 0.6 mg kg −1 (SD, 0.1)]. Mice with a score <3 were defined as ‘not in pain’, and a random set of these mice also received buprenorphine.
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28/06/2021· Acepromazine is a phenothiazine tranquilizer, with no analgesic activity and a long half-life. 64, 82, 83 Although some mice will typically reach a surgical anesthesia plane with the ket/xyl cocktail, acepromazine’s addition safely increases the percentage of mice reaching a surgical plane of anesthesia to acceptable levels.
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staff of the ULAR will be available to provide guidance in the care and use of animals regarding handling, immobilization, anesthesia, analgesia, tranquillization and euthanasia. 2. Implement protocols only as approved by the IACUC. Federal regulations and our internal institutional policies require that any deviation from the approved protocol ...
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10) Horton R, Hugunin, K, and Cotroneo T. 2008. ULAM Rat anesthesia and analgesia guidelines. University of Michigan, Ann Arbor. 11) Hrapkiewicz K, Medina L, Holmes D, Clinical Laboratory Animal Medicine 2nd ed. Iowa State University Press, Ames, Iowa, 1998. Title: Guidelines for Anesthesia and Analgesia in Mice Date: 9/28/07
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2. Considerations for Anesthesia and Analgesia, an Introduction (See Unit 1.4) Select the anesthetic based on the type of surgical procedure, the length of the surgical procedure, the equipment available and the expertise of those who will be responsible for administering the anesthetic (Flecknell, 1996; Kohn, 1997; Swindle, 2002).Consideration must also be given to …
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Depth of Anaesthesia. Depth of anesthesia should be monitored using a combination of autonomic reflex responses to noxious stimuli (heart rate and blood pressure) and electroencephalography (see section “Assessing anesthetic depth” below) if available. From: Nonhuman Primates in Biomedical Research (Second Edition), Volume 1, 2012.
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MOUSE ANESTHESIA AND ANALGESIA RECOMMENDATIONS 2 Non-painful procedures (e.g., imaging, restraint) Recommendations include: 1. Isoflurane: 3-4% for induction and 1-3% for maintenance. 2. Ketamine/xylazine: intraperitoneal dose at 70-100 mg/kg ketamine + 5-12 mg/kg xylazine.If
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retro-orbital [RO] orbital sinus) require sedation and/or analgesia). 3. Please refer to the Guidelines for Injections in Rodents and Rabbits, Virginia Tech Office of the University Veterinarian for recommended volumes and needles sizes. a. Tail Vein:0.5ml b. Retro-orbital Sinus:<0.15ml II. Personal Protective Equipment (PPE) and Hygiene a.
Chat OnlineThis document has been designed by the ULAM veterinary personnel as a guideline for sedation, anesthesia, and analgesia of laboratory mice. This is not intended to be an inclusive tutorial on all possible drug combinations that can be used in mice.
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The attending veterinarian can guide the IACUC in evaluating appropriate analgesia and anesthesia. In addition, Green (2003) , Machin (2001) , and Wright (2001) have reviewed some agents that have been shown to have analgesic properties in amphibians.
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However, the following concepts can guide the appropriate use of analgesia: Guidelines for Analgesia Moderate to Significant Pain The general recommendation for procedures likely to induce moderate to significant pain is to provide at least 48 hours of post-operative analgesia, and then additional analgesia as needed until the animal
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Coordinator to assure training requirements are met in accordance to IACUC Policy. 4. Attending veterinarian and/or designee: a. Provide guidance/oversight on surgery programs and post-surgical care. b. Provide consultation services to investigators on the appropriate choice of anesthetic and analgesic agents.
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